Yamaguchi Prefectural University BULLETIN of Faculty of Human Life Sciences

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Yamaguchi Prefectural University BULLETIN of Faculty of Human Life Sciences Volume 31
published_at 2005

Heat Shock Inhabits Autophosphorylation of Insulin Receptor at the Postbinding Level in Rat Hepatoma H4II Cells

熱ショックによるインスリン受容体自己リン酸化抑制の機序
Nagasaka Yuji
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Effects of heat shock on insulin signal transduction were examined using rat hepatoma H4EII(H4) cells. Exposure of cells to 45゜C for 10 min moderately activated ERK (Extracellular signal-regulated protein kinase), whereas strongly inhibit insulin…
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